Obesity Research Updates

Obese people face an increased risk of primary joint replacement die  to an increased waist circumference and body mass index  (BMI). These findings are emerging out of a research study conducted by the MonashUniversity, Melbourne, Australia which is published in Bio Med’s Central Open Access Journal. ‘Arthritis Research and Therapy’.

The team led by Flavia Cicuttini examined more than 32000 volunteers by looking at the relationship between different adiposity measures and the risk of subsequent primary knee and hip joint replacement. They found a three to four fold increased risk of primary joint replacement which is associated with body weight, BMI, fat mass and percentage fat. The researchers also came to the conclusion that both biomechanical and metabolic mechanisms associated with adiposity contribute to the risk of joint replacement.

It may be noted that adipose mass contributes to increased join loading which may increase the risk of Osteo Arthritis. The obesity epidemic occurring in developed countries is likely to have a significant impact on the future demands for knee and hip replacements for OA and understanding the mechanism of action may help in effective prevention of Osteo Arthritis.

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