Vaccine to help quit Smoking
Despite the known health risks, people continue to smoke and use tobacco primarily as a result of their addiction to nicotine. There is a well known fact that use of tobacco is the leading cause of preventable death and disabilities worldwide and nicotine is the main substance responsible for the addiction to tobacco. Most of the smokers who try to quit on their own fail on the long term.
Even different types of counseling and behavioral therapies can increase abstinence rates but can not tatally eliminate the habit. Similarly, pharmacotherapies prescribed in smoking cessation interventions, such as nicotine replacement products, bupropion and the recently approved varenicline, help smokers quit, but to a certain extent.
Based on these encouraging results, an exploratory phase II randomized trial were conducted on smokers who were ready to quit. A vaccine against nicotine was tested in a 6-month randomized, double blind phase II smoking cessation study in 341 smokers with a subsequent 6-month follow-up period. As per the report a significant success have been achieved. However, the safety analysis and effectiveness has to be studied on a larger group to ascertain evidence of efficacy and adverse events which are keys for vaccine to be approved by regulatory authority to be used by the consumer.
Tags: Vaccine , Smoking , Nicotine , Alum
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